- Flying high Nottingham Forest visit Aston Villa on Saturday
- Fulham welcome league leaders Liverpool on Sunday
- Leicester host Newcastle on Monday
Following a busy midweek schedule in the Premier League, the action continues with 10 top-flight matches happening over the weekend, wrapping up with Leicester welcoming Newcastle to the King Power Stadium on Monday night as they aim to break their seven-match losing streak.
One of the standout fixtures is the Manchester derby at Old Trafford on Sunday, while surprise package Nottingham Forest travels to Aston Villa for the Saturday evening kick-off.
Here is an overview of all 10 games with a score prediction for each.
Everton vs Arsenal (Saturday, 12.45pm)
Everton's unbeaten run of 10 matches came to an end with a 1-0 defeat against Liverpool, but they have the chance to bounce back against Arsenal.
Both teams have been drawing matches recently, with Everton sharing points in five of their last seven games and Arsenal having back-to-back draws in their away fixtures.
Score prediction: Everton 1-1 Arsenal
Crystal Palace vs Brighton (Saturday, 3pm)
Brighton suffered a 3-0 defeat to Aston Villa but have the opportunity to respond with a strong performance against Crystal Palace.
Crystal Palace has only lost three of their last 18 league matches, and a draw would not be surprising given that 1-1 has been a common scoreline in their recent encounters.
Score prediction: Crystal Palace 1-1 Brighton
Ipswich vs Wolves (Saturday, 3pm)
Ipswich must secure a victory against Wolves to keep their survival hopes alive as they trail behind in the standings.
However, with Wolves winning four of their last seven matches and Ipswich struggling at home, it looks like an uphill battle for the Tractor Boys.
Score prediction: Ipswich 1-2 Wolves
West Ham vs Bournemouth (Saturday, 3pm)
Bournemouth's winless streak continues as they face West Ham, who have had an extra day of rest and preparation.
The Cherries have been losing steam with consecutive 2-1 defeats, while West Ham looks to capitalize on their opponent's struggles.
Score prediction: West Ham 2-1 Bournemouth
Aston Villa vs Nottingham Forest (Saturday, 5.30pm)
In-form Aston Villa, unbeaten in their last 14 home league games, take on Nottingham Forest, who have stumbled in their away matches recently.
Nottingham Forest will have a tough challenge ahead as they face a solid Aston Villa side.
Score prediction: Aston Villa 2-0 Nottingham Forest
Brentford vs Chelsea (Sunday, 2pm)
Chelsea might be vulnerable against Brentford, who have a decent record against their London rivals in recent encounters.
Chelsea's struggles away from home could play into Brentford's hands in this matchup.
Score prediction: Brentford 2-1 Chelsea
Fulham vs Liverpool (Sunday, 2pm)
League leaders Liverpool, with a strong recent record, face Fulham who have shown inconsistency in their home matches.
Liverpool are expected to dominate the game with their solid performances on the road.
Score prediction: Fulham 0-2 Liverpool
Tottenham vs Southampton (Sunday, 2pm)
Tottenham, despite focusing on their Europa League commitments, should have enough quality to defeat Southampton.
Southampton, struggling this season, will be aiming to make an impact but are likely to face a tough challenge against Tottenham.
Score prediction: Tottenham 3-1 Southampton
Manchester United vs Manchester City (Sunday, 4.30pm)
Manchester United have had the upper hand in recent derbies against Manchester City, who have shown inconsistencies in their away form.
Manchester United's improving performances could be a deciding factor against a City side missing their key striker.
Score prediction: Manchester United 2-1 Manchester City
Leicester vs Newcastle (Monday, 8pm)
Leicester faces a tough challenge against a confident Newcastle side chasing a top-four spot after their recent cup success.
Score prediction: Leicester 0-2 Newcastle